Thirsty Pathogen is an adult RPG Maker adventure by Silent Pyramid, using animated 2D and 3DCG visuals. You play Ethan, who wakes alone in an abandoned hospital in the ruined city of New Kroy. His father was laid off, his sister vanished two years ago, and his hopes for a quiet adult life lie broken. He eventually finds her, but she does not speak or recognize him, and parts of her body are marked by strange ashy patches. The story mixes horror and corruption as Ethan tries to endure and protect the few survivors.
The game remains in development at version v0.3f, released September 24, 2024. It runs on Windows in English and is uncensored. The latest changelog fixes generator connection by replacing the old option menu with a simpler color-matching puzzle, while the hack option is temporarily removed. It also resolves a game freezing problem through a suggested plugin and corrects the Cancel option in Lori's room so the image no longer freezes.
Developer's description
Imagine waking up in your hospital room and no one around. What's more, the whole hospital looks abandoned, and all of New Kroy is in ruins.
That's the fate that met Ethan. A couple of months ago, his father was laid off from his job. His sister disappeared 2 years ago, and the search for her led nowhere. The adult world he aspired to lies beneath his feet and somewhere in the far away fallen buildings, just like his dreams and goals of his quiet life. In this chaos he was able to find his sister, who doesn't even recognize him, doesn't talk at all, and half of her body is covered in mysterious ashy spots.
Is it war? Or have we been attacked by terrorists? Why did my sister only show up now and what happened to her? So many questions and no answers...
Now, in this empty and ruined city, he must fight to survive and protect those left alive in this ruthless and dangerous world
v0.3f
1) Fixed the issue where you couldn't connect generators, because menu with options disappeared. Now, there's a simpler puzzle where you just need to connect the right colors to the generators. The option to "hack" this puzzle has been temporarily removed
2) The game freezing issue has been fixed. Thanks to everyone who suggested the right plugin to fix the mhz problem in the game
3) The issue with the "Cancel" option in Lori's room has been fixed. The image won't freeze anymore
v0.3e
1. Fixed the issue where you couldn't close the paper that Jill showed you about Aqua.
v0.3d
// I've been really late with the 0.3 update release, and those who check the Discord chat know my personal issues I've been dealing with. I won't make any more promises because life is so unpredictable
I heard your feedback and I'm sorry that the puzzle with the generators was too difficult for most players. In the prologue, you can now remember the door code to the generator room (requires Intellect 1) and "hack" the generator codes (requires Strength 1)
90+ New Renders
2 New Characters
3 New Quests
6 New Locations
New Map for Scavenging and more
Added a Gallery. You can view all the available scenes in the game by accessing the MC's computer in his room. The access code known "Infected" patrons of SubscribeStar and above
Added an option to spy on girls through the security cameras (except Emma)
Added an option to lockpick the entrance to the girls room and “play” with them (available only Jill and Lori for now)
Fixed the font size of the names. Now this text should not be cut off at the bottom
Changed old icons for items
Added an option to interact with the girls and increasing their "Corruption" points. There's placeholders for special scenes while you corrupting. In future update I'll add new scenes
Now there's the effects of hunger and thirst on the girls. If you have no food or water, the girls won't be in the mood to "play" with you. You also can't run (shift key) because of no food or water in bunker
Added an option to craft some items and upgrades for the bunker
Combat system has been simplified. New formula:
If Strength < 5, you have 5,3 seconds to complete QTE event with 4 inputs
If Strength < 20, you have 6 seconds to complete QTE event with 3 inputs
If Strength > 50, you have 6,6 seconds to complete QTE event with 2 inputs
Note: If you attacked from behind with knife - instant kill
Some minor changes that I've forgot
==================
v0.2a
// This huge delay is because of my personal life issues. I broke up with my girl, lost a family member, and been hella busy with my IRL job... On top of that, the game didn't have the necessary mechanics for the story to continue, and that took a lot of time. Finally, I can give you guys a small update. Future updates shouldn't take this long. Thanks for your patience, units!
Minor texts orthographic corrections (Sorry for that, english is not my native language)
Fixed the false positive issue with the antivirus. Shouldn't be any problems now
Minor changes for Quests log
Added button "Exit" in title menu
Removed mentions about Patreon. Now the only platform to support this game is SubscribeStar
New icons for items
You can now change your name (available at computer in your room)
Changed the relationships between characters:
Emma is your sister (in game "Sister")
Lori is your mother (in game "Mom")
Note: These changes cannot be modified, they are based on the lore of the game. So "Landlady" and "Roommate" was exclusive for Patreon only
Now you can see how currupted girls are by pressing "C" (This information will be transferred to the HUD in next update)
New HUD:
Time of day
Amounts of Food
Water and Materials
Added cheat menu (available at computer in your room)
Edit corruption points
Edit base supplies (water, food, materials)
"God Mode" cheat
"Supply" cheat
Note: Only people in SubscribeStar of tier "Survivor" and above have code for access to use this cheats
New features: Lock picking, Supplies scavenging, Bunker Supplies, Fighting
Lock picking works on this formula:
If Intellect < 5, you have 5 seconds to complete QTE event with 6 inputs
If Intellect < 20, you have 5 seconds to complete QTE event with 5 inputs
If Intellect > 50, you have 5 seconds to complete QTE event with 4 inputs
Note: Each attempt uses one of your lock picks. If you run out of them, you won't be able to pick the lock
Supplies scavenging works on this formula:
If Intellect < 5, chances to find something = 50%
If Intellect < 20, chances to find something = 75%
If Intellect > 50, chances to find something = 100%
Note: Food and Water from 5 to 20; Materials from 1 to 10
Bunker Supplies decrease each time you sleep. Here's a formula:
Food & Water - (Survivors count * Cost - Bunker upgrades)
Note: Survivors count = Number of people living in bunker (including you), Cost = The quantity of supply being handed out. Constantly equals "2", Bunker upgrades = Specific upgrades of your bunker increase this number by 1. Without upgrades = 0
Fighting works on this formula:
If Strength < 5, you have 5 seconds to complete QTE event with 5 inputs
If Strength < 20, you have 6 seconds to complete QTE event with 4 inputs
If Strength > 50, you have 7 seconds to complete QTE event with 3 inputs
Note: If you attacked from behind with knife - instant kill
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v0.1b
- Minor fixes
- Added save points
- Added hint in generator quest (bunker)
- Now mouse control works in game
- Updated nw.js (fix for popup about profile)
==================
v0.1a
First release
Player reviews
Player rating4.5 / 5 · 6 ratings
Written reviews6 · avg 4.2★
Positive (4–5★)67%
Latest review2026-02-24
What players say
Mostly positive reviews praise atmosphere and art, while some find writing and gameplay weak.
5★3
4★1
3★2
2★0
1★0
Players like
Atmospheric post-apocalyptic setting and handcrafted world
Good artwork, CGs, and character models
Easy puzzles with nice variety
Resource gathering and light survival elements
Common complaints
Weak writing and basic plot
Some puzzles require manual notes or outside searching
Gameplay can feel slow and movement-focused
Best for players who enjoy atmospheric post-apocalyptic art, puzzles, and light survival.
Summarised from 6 written player reviews.
4-kun2026-02-24★★★★★
Well, let’s get this out of the way: the writing is basically nonexistent, so don’t expect much. Things just happen, and characters behave a certain way… just because. That’s it. On the other hand, so far the world is handcrafted…
lhucio2024-10-10★★★★★
I have played 1.5 hours, and when I say played I mean going from point A to point B. As a VN it has potential with a few fixes, as a game not so much. The atmosphere is well handled…
Azure_Lightning2024-10-08★★★★★
I think it's a great idea to explore in the narrative. I really love the perspective you take, especially in a post-apocalyptic world. Even with that setting, family bonds are something I always look for when deciding to play this…